A Practical, Judgment-Free Option for Alcohol Use Disorder
If the holidays tend to increase your drinking, you're not alone. The Sinclair Method (TSM) is a medication-assisted approach that can help you reduce or stop drinking—without requiring complete abstinence from day one.
What is the Sinclair Method?
The Sinclair Method is a science-based treatment for Alcohol Use Disorder (AUD) that uses naltrexone, a medication that blocks the endorphin reward alcohol triggers in the brain. Over time, this breaks the learned association between alcohol and pleasure—a process called pharmacological extinction—which naturally reduces cravings and drinking.
Key concept: You take naltrexone only before you drink (typically one hour prior), not every day.
How Does It Work?
Alcohol triggers endorphin release that strengthens the habit loop: "Drink → feel better → repeat." Naltrexone blocks those receptors, preventing the usual reward response. With consistent use, your brain learns that alcohol is less rewarding—and cravings typically fade over weeks to months.
What to Expect
Week 1–2
- Take naltrexone 50 mg one hour before your first drink
- Keep a drink log
- Mild side effects may include nausea, headache, or sleep changes
Week 3–6
- Lower urges, fewer drinks per occasion
2–3 Months and Beyond
- Cravings and drinking often decline substantially
The Golden Rule of TSM
Never drink without naltrexone. Drinking without medication can re-strengthen the habit loop.
Who Is a Good Candidate?
- Adults with mild to severe AUD who want a harm-reduction approach
- People who have tried to cut down before and struggle with cravings
- Those who prefer a private, at-home approach
Holiday Game Plan on TSM
- Dose early — set a reminder: naltrexone 60 minutes before drinking
- Pre-commit your limits — decide your max drinks before you arrive
- Create escape routes — drive yourself, set an end time
- Watch your triggers — plan breaks and check-ins
- Keep your log — track progress
Ready to Explore The Sinclair Method?
Berkley Wellness — Integrated, judgment-free care for alcohol use, mental health, and wellness. Call (254) 212-8014.